Anyone with a compromised
immune system or is more prone to getting sick and fatigued.
Especially true when stress is great and immune system is overloaded
. Mushrooms are also very beneficial for managing a wide variety of
viruses and pathogens. They are also used in the treatment of immune
imbalances in fertility treatments.
For anyone who is undergoing treatment
in fertility clinics and have not been successful but have not found
any reason for failure, please read on.
causes of implantation failure
a relatively new diagnostic medicine within IVF centres, which has
advances in the last 5-10 years. It is still is in its infancy in
Ireland and is being
American IVF centres it is part of the general initial workup of
woman has signs of gross inflammation it is recommended early, but
offered if 3 failed cycles.
normal pregnancy a womans’s body accommodates what is essentially a
body that should be destroyed by her immune system.
normal immune system is balanced between Th1 ‘
and Th2 ‘suppressive’ response Most women have a balanced system.
Women with implantation failures or recurrence miscarriage have an unbalanced immune system. They are too Th1 activated with cells that attack their pregnancy and /or too Th2 compromised lacking protective antibodies” (extract taken from “The body at War” by John Dwyer).
The mother’s immune system identifies the fetal cells as intruder and the mother’s immune system reacts against it.
of the egg
female immune system attacks the egg in the ovary, the
embryo in the fallopian tubes or at the implantation site
or disrupting implantation.
at the Endometrium implantation site
female immune system fails to cloak and protect the
site from attack – male or female initiated
the sperm has antigen which triggers her immune
NOT to reject but if this is interfered with by the disruption to the
response then this causes dif ficulties.
helper cells (
Th cells) are a type of T cell that plays an important part in the
immune system especially in “adaptive” immune system. They help
the activity of other immune cells by releasing T Cell Cytokines.
cells help suppress or regulate immune responses. They are essential
to B Cell antibody class switching and in the activation and growth
of cytotoxic T cells and in maximizing bacterial activity of
phagocytosis such as the action of Macrophages.
Th cells express surface protein CD4 and are called CD4+T cells.
cells are treated as having a Pre-de fined role as helper T cells
within the immune system
helper cells produce Interferon, Gamma interleukin (IL2) and tumour
necrosis factor (TNF)beta, which activate Macrophages and are
responsible for cell mediated immunity and phagocyte dependent
Th1 cell mainly develop after infection by intercellular bacteria and some viruses. Th2 cells predominate in responses to infections by gastrointestinal toxins
Th1 cells are involved in pathogenesis of organ specific autoimmune disorders such as Crohns, Helicobacter pylori induced peptic ulcer, and unexplained recurrent miscarriages.
the antibody forming cells of the immune system. They are found in
blood, lymph nodes, spleen, tonsil and other mucosal tissues.
a large group of proteins, peptides or glycoproteins that are
secreted by specific cells of the immune system. They are molecules
that regulate immunity and inflammation.
assist cell to cell communication in immune responses and stimulate
moving of cells towards site of inflammation and infection and
trauma. They are important regulators in the immune system.
Killer cells are
are a subset of lymphocytes and are involved in the innate immune
responses and play an important role in the defense against viral
infections, tumours and when raised above normal can prevent
implantation of the embryo.
In Sims IVF clinic in Dublin, the
laboratory has created specific tests called the Zip blood test and
ZFB endometrial biopsy which tests for the specific imbalances of the
immune system, as mentioned in the previous page. There are several
other detailed tests which check for various other changes and
discrepancies. They offer within the clinic particular treatments
which involve taking oral steroids, and other immune suppressant
Natural immune regulation
Acupuncture is used to regulate the
immune system alone. Its action can be complemented by use of
for regulation of the immune system by way of the adaptogenic quality
of each mushroom. According to TCM mushrooms assist by way of
tonification of Qi, Blood, Yin, Yang, and Jing in Fertility
have been part of the culture of TCM for thousands of years, but in
more recent years have been accepted by western medicine, due modern
enhancing plants and mushrooms have been studied by Japanese
researchers since the 1960’s.
are used to restore the immune system of patients with tumours,
increasing the white blood cells and deficiency of platelets, both
resulting from chemotherapy.
adaptogenic qualities help to regulate various immune related
disorders. They also raise the general core energetic stamina of the
mushrooms used to help Fertility disorders –
Coriolus MRL (Turkey Tail mushroom)
Tindall an acupuncturist working in London with HIV patients, in 1999
confirmed that Coriolus-MRL produced marked improvement in CD4 levels
and viral load. They are used in more recent years in the regulation
of unstable immune systems in fertility patients.
shift, Leaky gut syndrome, chronic fatigue syndrome, anti- viral
action on Epstein-Barr virus, and in Human papillo virus.
in Lung disorders, liver and kidney yin deficiency, phlegm
obstructing meridians, and lungs. Spleen qi deficiencies. Nourishes
the heart and spirit.
MRL cordyceps sinensis
fungus is derived from a master strain of Cordyceps sourced from high
altitudes in Tibet and Nepal. It parasites on the larvae of the
Lepidoptera moth, and during each Spring grows into a finger shaped
fruiting body. The MRL raw material is not harvested from dead
diseases, asthma, eczema, autoimmune disorders, antidepressant and
anti-stress action, regulates hormones. Hypoglycaemic action and used
in insulin resistant patients.
support especially in cirrhosis, and regenerates liver tissue.
the lungs in Lung Yin Deficiency and defensive qi, Kidney Yang
deficiency. Restores sexual vitality an used traditionally for
longevity and to treat impotence.
MRL (ganoderma/ Lingzhi) – grows on mouldering trunks and stumps in
the coastal regions of China.
is known as a plant of immortality or a plant of spiritual power, and
for centuries has been valued in China and Japan. Uses
bronchitis, allergy, resolves phlegm, antihistamine, Chronic Fatigue
syndrome. Lowers blood pressure. Boosts the immune system, antiviral,
anti-inflammatory. Liver protection regeneration and detoxification
in Tumour diseaases, and lowers toxic side effects of chemo and
T and B lymphocytes, suppressing the expanding of Tumour cells.
Supports cell renewal in bone marrow and white lymphocytes and
erythrocytes, NK cells.
in fertility treatments to regulate the immune system, acting as
immuno stimulants, antibacterial, antiviral. Reduces allergy and
inflammation and major depletion and exhaustion.
the Heart and Calms the Spirit. Nourishes all Qi Deficiencies in TCM-
Liver, Kidney, Lung, Heart, Spleen, Stomach, Blood, Jing
Meshimakobu (the black hoof mushroom /Sang huang)
is so-called due to its hoof shape. It is primarily found in Asian
countries such as China, Japan, and Korea.
a basidiomycete fungus, this mushroom often grows in large numbers on
Phellinus linteus has a distinct bitter taste. As such, it is usually
consumed in the form of a medicinal tea in Korea. Notably, the
mushroom is regarded as a medicine that can promote health and
longevity in traditional Asian cultures.
consumed regularly, the mushroom has been found to treat and prevent
a diverse range of ailments such as diarrhea, hemorrhages, gastro
enteric dysfunction, and certain cancers. It possesses the greatest
concentration of anti-tumor properties. This makes it an ideal as an
anti-cancer drug. Over the past decade, Korean scientists have been
researching on the mushroom’s possible ability of improving the
body’s immunity and of enhancing the effects of chemotherapy.
wound healing, anti-viral, anti-inflammatory, antioxidant,and
Phellinus linteus has been shown to be a possible treatment for
cancer, specifically breast, prostate, bladder, bone, and lung
cancer, bowel more research has to be conducted in order to obtain
conclusive evidence of its efficacy.
general though, the extract from the mushroom have been known to
suppress metastasis and the growth of tumors, stimulate the cell’s
immune defense, and lessen inflammation.
some studies, marked improvement was witnessed in cancer patients who
consumed the mushroom in conjunction with other treatments.
and anti-inflammatory, adaptogenic
suffering from rheumatoid arthritis were able to experience markedly
less inflammation in their joints after consuming the polysaccharide
extract from the edible fruit of the Phellinus linteus. Their
autoimmune responses also lessened greatly. Anti- inflammatory agent
especially in cases of septic shock that are caused by
studies have proven that the polysaccharides of Phellinus linteus are
highly effective in treating immune imbalances and allergic
the active components in the mushroom are capable of suppressing Th2
cytokines and conversely inducing secretion of Th1 cytokines that are
known to promote a more balanced immune system.
the release of histamine in the body even after the introduction of
known allergic stimuli. Useful in atopic dermatitis or asthma.
women who have elevated levels of NK cells and cytokine often suffer
from infertility issues. Consuming Phellinus linteus has been shown
to lower these components and thus increase the chances of successful